Clinically tested blend of All- Trans Retinol and Trichloroacetic Acid (TCA) to maintain and enhance the skin’s youthful appearance.
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Description
Clinically tested formulation of 1% Micro-encapsulated All-Trans Retinol combined with TCA helps reduce signs of aging while brightening complexion.
- Trichloroacetic acid (TCA) helps improve skin discoloration, balance tone and pore size.
- Irritation associated with retinol is reduced via hydrating ingredients including Hyaluronic acid and Squalane
- Micro-encapsulated All-trans retinol delivers extensive anti-aging benefits and conditions for improved skin health
Directions For Use
Apply a thin layer to the face, neck, and décolleté at night. Follow with your normal skincare regimen.
Key Ingredients
- All-trans Retinol 1% micro-encapsulated concentration reduces the appearance of the negative effects of collagen degradation with little to no irritation.
- Trichloroacetic Acid improves the appearance of skin discoloration, pore size, and uneven texture.
- Hyaluronic Acid, Shea Butter and Squalane restores and improves skin’s moisture level.
Clinical test results
Median percent improvement scores compared to baseline ranged from 33% to 50% at 4, 8, and 12 weeks for radiance, tone, smoothness, texture, and overall appearance. Values were more variable for red/blotchy and consistently 0 for dryness, the latter due to the small range of scores (0 to 1). Percent improvement for 4, 8, and 12 weeks compared to baseline was calculated by the following formula, using 12-weeks as an example
Improvements at 12 weeks were significant for texture (p = 0.0013), tone (p = 0.0002), glow (p = 0.0013), smoothness (p = 0.0031), youthful appearance (p = 0.0026), pores (p = 0.0038), and satisfaction (p = 0.0002). The percentage of subjects improved for these parameters ranged from 57.1% to 85.7%. For the remaining skin parameters, percentages of subjects improved at 12 weeks ranged from 38.1% (lines and wrinkles, discoloration) to 61.9% (redness and broken capillaries).
The findings of the present study support these expected clinical benefits and tolerability. The Investigator’s objective assessments show that use of the Test Product as in the present study provides significant improvement in radiance, tone, smoothness, texture, and overall appearance and that improvement increases with continued use up to 12 weeks. These results are paralleled by the steady increase in the percentage of subjects improved during the study period. Improvement in red/blotchy became significant at 8 weeks and remained significant at 12 weeks with 61.9% of subjects improved.
Subjective skin quality assessments addressed changes in the same skin parameters (texture, tone, radiance [glow], smoothness, dryness, discoloration) with consideration also given to pores and overall satisfaction. As with the Investigator’s objective assessments,
Discussion
As stated earlier, the Test Product is a combination of all-trans retinol, HA, and TCA for the treatment of skin aging, discoloration, and hydration. Squalene and shea butter are also present. All-trans retinol (1%) supports collagen with little or no irritation and is encapsulated for stability and skin penetration. TCA improves the appearance of skin discoloration, pore size, and uneven texture. HA restores and improves skin moisture.
